Newcastle Structural Biology Laboratory

Newcastle Structural Biology lab was founded in 2003 and much of the laboratory's core activity centres on important questions in microbial lifestyles:

How do they respond to changes in their environment?

How do they ensure the faithful passage of their genetic material?

How do they build the protective wall that protects the cell?

We primarily use X-ray crystallography to solve the structures of proteins and protein complexes that are central to these questions. This is complemented with electron microscopy, biochemistry and cell biology to help us answer all the questions that these systems pose. There are currently three research groups in the Newcastle Structural Biology Laboratory, those of Rick Lewis, Susan Firbank and Jon Marles-Wright. For further information on their individual research interests or our facilities please click on the names in the menu bar.