Arnaud Basle’s publications

  1. Wang, P, Li, J, Li, T, Li, K, Ng, PC, Wang, S et al.. Molecular principles of the assembly and construction of a carboxysome shell. Sci Adv. 2024;10 (48):eadr4227. doi: 10.1126/sciadv.adr4227. PubMed PMID:39612341 PubMed Central PMC11606499.
  2. Pastok, MW, Tomlinson, CWE, Turberville, S, Butler, AM, Baslé, A, Noble, MEM et al.. Structural requirements for the specific binding of CRABP2 to cyclin D3. Structure. 2024;32 (12):2450. doi: 10.1016/j.str.2024.10.027. PubMed PMID:39489909 .
  3. Pastok, MW, Tomlinson, CWE, Turberville, S, Butler, AM, Baslé, A, Noble, MEM et al.. Structural requirements for the specific binding of CRABP2 to cyclin D3. Structure. 2024;32 (12):2301-2315.e6. doi: 10.1016/j.str.2024.09.020. PubMed PMID:39419021 .
  4. Blomgren, LKM, Huber, M, Mackinnon, SR, Bürer, C, Baslé, A, Yue, WW et al.. Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase. Nat Commun. 2024;15 (1):3248. doi: 10.1038/s41467-024-47174-y. PubMed PMID:38622112 PubMed Central PMC11018872.
  5. McCorvie, TJ, Adamoski, D, Machado, RAC, Tang, J, Bailey, HJ, Ferreira, DSM et al.. Architecture and regulation of filamentous human cystathionine beta-synthase. Nat Commun. 2024;15 (1):2931. doi: 10.1038/s41467-024-46864-x. PubMed PMID:38575566 PubMed Central PMC10995199.
  6. Helena-Bueno, K, Rybak, MY, Ekemezie, CL, Sullivan, R, Brown, CR, Dingwall, C et al.. A new family of bacterial ribosome hibernation factors. Nature. 2024;626 (8001):1125-1132. doi: 10.1038/s41586-024-07041-8. PubMed PMID:38355796 PubMed Central PMC10901736.
  7. Silale, A, Zhu, Y, Witwinowski, J, Smith, RE, Newman, KE, Bhamidimarri, SP et al.. Dual function of OmpM as outer membrane tether and nutrient uptake channel in diderm Firmicutes. Nat Commun. 2023;14 (1):7152. doi: 10.1038/s41467-023-42601-y. PubMed PMID:37932269 PubMed Central PMC10628300.
  8. Paloyan, A, Sargsyan, A, Karapetyan, MD, Hambardzumyan, A, Kocharov, S, Panosyan, H et al.. Structural and biochemical characterisation of the N-carbamoyl-β-alanine amidohydrolase from Rhizobium radiobacter MDC 8606. FEBS J. 2023;290 (23):5566-5580. doi: 10.1111/febs.16943. PubMed PMID:37634202 PubMed Central PMC10952681.
  9. Abellon-Ruiz, J, Jana, K, Silale, A, Frey, AM, Baslé, A, Trost, M et al.. BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B12 uptake in gut Bacteroides. Nat Commun. 2023;14 (1):4714. doi: 10.1038/s41467-023-40427-2. PubMed PMID:37543597 PubMed Central PMC10404256.
  10. White, JBR, Silale, A, Feasey, M, Heunis, T, Zhu, Y, Zheng, H et al.. Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes. Nature. 2023;618 (7965):583-589. doi: 10.1038/s41586-023-06146-w. PubMed PMID:37286596 .
  11. Ashley, B, Baslé, A, Sajjad, M, El Ashram, A, Kelis, P, Marles-Wright, J et al.. Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C-C Bond-Forming α-Oxoamine Synthase. ACS Sustain Chem Eng. 2023;11 (21):7997-8002. doi: 10.1021/acssuschemeng.3c00243. PubMed PMID:37266354 PubMed Central PMC10230504.
  12. Agirre, J, Atanasova, M, Bagdonas, H, Ballard, CB, Baslé, A, Beilsten-Edmands, J et al.. The CCP4 suite: integrative software for macromolecular crystallography. Acta Crystallogr D Struct Biol. 2023;79 (Pt 6):449-461. doi: 10.1107/S2059798323003595. PubMed PMID:37259835 PubMed Central PMC10233625.
  13. Al-Jourani, O, Benedict, ST, Ross, J, Layton, AJ, van der Peet, P, Marando, VM et al.. Identification of D-arabinan-degrading enzymes in mycobacteria. Nat Commun. 2023;14 (1):2233. doi: 10.1038/s41467-023-37839-5. PubMed PMID:37076525 PubMed Central PMC10115798.
  14. Lee, J, Dalton, RA, Baslé, A, Vita, N, Dennison, C. Important Structural Features of Thiolate-Rich Four-Helix Bundles for Cu(I) Uptake and Removal. Inorg Chem. 2023;62 (17):6617-6628. doi: 10.1021/acs.inorgchem.2c04490. PubMed PMID:37057906 PubMed Central PMC10155185.
  15. Sendra, KM, Barwinska-Sendra, A, Mackenzie, ES, Baslé, A, Kehl-Fie, TE, Waldron, KJ et al.. An ancient metalloenzyme evolves through metal preference modulation. Nat Ecol Evol. 2023;7 (5):732-744. doi: 10.1038/s41559-023-02012-0. PubMed PMID:37037909 PubMed Central PMC10172142.
  16. Calò, P, Pianton, N, Basle, A, Vasiljevic, A, Barritault, M, Beuriat, PA et al.. Bevacizumab as Single Agent in Children and Teenagers with Optic Pathway Glioma. Cancers (Basel). 2023;15 (4):. doi: 10.3390/cancers15041036. PubMed PMID:36831379 PubMed Central PMC9954224.
  17. van den Berg, B, Silale, A, Baslé, A, Brandner, AF, Mader, SL, Khalid, S et al.. Structural basis for host recognition and superinfection exclusion by bacteriophage T5. Proc Natl Acad Sci U S A. 2022;119 (42):e2211672119. doi: 10.1073/pnas.2211672119. PubMed PMID:36215462 PubMed Central PMC9586334.
  18. Crouch, LI, Urbanowicz, PA, Baslé, A, Cai, ZP, Liu, L, Voglmeir, J et al.. Plant N-glycan breakdown by human gut Bacteroides. Proc Natl Acad Sci U S A. 2022;119 (39):e2208168119. doi: 10.1073/pnas.2208168119. PubMed PMID:36122227 PubMed Central PMC9522356.
  19. Krissinel, E, Lebedev, AA, Uski, V, Ballard, CB, Keegan, RM, Kovalevskiy, O et al.. CCP4 Cloud for structure determination and project management in macromolecular crystallography. Acta Crystallogr D Struct Biol. 2022;78 (Pt 9):1079-1089. doi: 10.1107/S2059798322007987. PubMed PMID:36048148 PubMed Central PMC9435598.
  20. Luis, AS, Baslé, A, Byrne, DP, Wright, GSA, London, JA, Jin, C et al.. Author Correction: Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota. Nat Chem Biol. 2022;18 (9):1032. doi: 10.1038/s41589-022-01132-1. PubMed PMID:35931865 .
  21. Heaver, SL, Le, HH, Tang, P, Baslé, A, Mirretta Barone, C, Vu, DL et al.. Characterization of inositol lipid metabolism in gut-associated Bacteroidetes. Nat Microbiol. 2022;7 (7):986-1000. doi: 10.1038/s41564-022-01152-6. PubMed PMID:35725777 PubMed Central PMC9246714.
  22. Luis, AS, Baslé, A, Byrne, DP, Wright, GSA, London, JA, Jin, C et al.. Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota. Nat Chem Biol. 2022;18 (8):841-849. doi: 10.1038/s41589-022-01039-x. PubMed PMID:35710619 PubMed Central PMC7613211.
  23. Ling, EM, Baslé, A, Cowell, IG, van den Berg, B, Blower, TR, Austin, CA et al.. A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193. Structure. 2022;30 (8):1129-1145.e3. doi: 10.1016/j.str.2022.05.009. PubMed PMID:35660158 PubMed Central PMC9592559.
  24. Lanzoni-Mangutchi, P, Banerji, O, Wilson, J, Barwinska-Sendra, A, Kirk, JA, Vaz, F et al.. Structure and assembly of the S-layer in C. difficile. Nat Commun. 2022;13 (1):970. doi: 10.1038/s41467-022-28196-w. PubMed PMID:35217634 PubMed Central PMC8881574.
  25. Ross, J, McIver, Z, Lambert, T, Piergentili, C, Bird, JE, Gallagher, KJ et al.. Pore dynamics and asymmetric cargo loading in an encapsulin nanocompartment. Sci Adv. 2022;8 (4):eabj4461. doi: 10.1126/sciadv.abj4461. PubMed PMID:35080974 PubMed Central PMC8791618.
  26. Bhamidimarri, SP, Young, TR, Shanmugam, M, Soderholm, S, Baslé, A, Bumann, D et al.. Acquisition of ionic copper by the bacterial outer membrane protein OprC through a novel binding site. PLoS Biol. 2021;19 (11):e3001446. doi: 10.1371/journal.pbio.3001446. PubMed PMID:34762655 PubMed Central PMC8610252.
  27. Luis, AS, Jin, C, Pereira, GV, Glowacki, RWP, Gugel, SR, Singh, S et al.. A single sulfatase is required to access colonic mucin by a gut bacterium. Nature. 2021;598 (7880):332-337. doi: 10.1038/s41586-021-03967-5. PubMed PMID:34616040 PubMed Central PMC9128668.
  28. van den Berg, B, Pedebos, C, Bolla, JR, Robinson, CV, Baslé, A, Khalid, S et al.. Structural Basis for Silicic Acid Uptake by Higher Plants. J Mol Biol. 2021;433 (21):167226. doi: 10.1016/j.jmb.2021.167226. PubMed PMID:34487790 .
  29. Barritault, M, Poncet, D, Meyronet, D, Vasiljevic, A, Lopez, J, Descotes, F et al.. NTRK2 gene fusion and resistance mutation: Seventeen-year course of a paediatric glioma. Pediatr Blood Cancer. 2021;68 (9):e29114. doi: 10.1002/pbc.29114. PubMed PMID:34003575 .
  30. Salamina, M, Montefiore, BC, Liu, M, Wood, DJ, Heath, R, Ault, JR et al.. Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation. J Mol Biol. 2021;433 (5):166795. doi: 10.1016/j.jmb.2020.166795. PubMed PMID:33422522 PubMed Central PMC7895821.
  31. Gray, DA, White, JBR, Oluwole, AO, Rath, P, Glenwright, AJ, Mazur, A et al.. Insights into SusCD-mediated glycan import by a prominent gut symbiont. Nat Commun. 2021;12 (1):44. doi: 10.1038/s41467-020-20285-y. PubMed PMID:33398001 PubMed Central PMC7782687.
  32. Somboon, K, Doble, A, Bulmer, D, Baslé, A, Khalid, S, van den Berg, B et al.. Uptake of monoaromatic hydrocarbons during biodegradation by FadL channel-mediated lateral diffusion. Nat Commun. 2020;11 (1):6331. doi: 10.1038/s41467-020-20126-y. PubMed PMID:33303757 PubMed Central PMC7728783.
  33. Duan, CJ, Baslé, A, Liberato, MV, Gray, J, Nepogodiev, SA, Field, RA et al.. Ascertaining the biochemical function of an essential pectin methylesterase in the gut microbe Bacteroides thetaiotaomicron. J Biol Chem. 2020;295 (52):18625-18637. doi: 10.1074/jbc.RA120.014974. PubMed PMID:33097594 PubMed Central PMC7939467.
  34. Moreau, A, Marie, E, Bonneville-Levard, A, Basle, A, Kryza, D. Skull vault hemangioma mimicking neoplastic lesion on [68Ga]Ga-PSMA-11 PET/CT in a patient with glioblastoma: A case report. Radiol Case Rep. 2020;15 (12):2598-2601. doi: 10.1016/j.radcr.2020.10.005. PubMed PMID:33088371 PubMed Central PMC7557882.
  35. Piergentili, C, Ross, J, He, D, Gallagher, KJ, Stanley, WA, Adam, L et al.. Dissecting the structural and functional roles of a putative metal entry site in encapsulated ferritins. J Biol Chem. 2020;295 (46):15511-15526. doi: 10.1074/jbc.RA120.014502. PubMed PMID:32878987 PubMed Central PMC7667983.
  36. Ndeh, D, Baslé, A, Strahl, H, Yates, EA, McClurgg, UL, Henrissat, B et al.. Author Correction: Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus. Nat Commun. 2020;11 (1):4396. doi: 10.1038/s41467-020-18097-1. PubMed PMID:32859948 PubMed Central PMC7455702.
  37. Crouch, LI, Liberato, MV, Urbanowicz, PA, Baslé, A, Lamb, CA, Stewart, CJ et al.. Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown. Nat Commun. 2020;11 (1):4017. doi: 10.1038/s41467-020-17847-5. PubMed PMID:32782292 PubMed Central PMC7419316.
  38. Assaad, S, Avrillon, V, Fournier, ML, Mastroianni, B, Russias, B, Swalduz, A et al.. High mortality rate in cancer patients with symptoms of COVID-19 with or without detectable SARS-COV-2 on RT-PCR. Eur J Cancer. 2020;135 :251-259. doi: 10.1016/j.ejca.2020.05.028. PubMed PMID:32540204 PubMed Central PMC7275994.
  39. Barwinska-Sendra, A, Garcia, YM, Sendra, KM, Baslé, A, Mackenzie, ES, Tarrant, E et al.. An evolutionary path to altered cofactor specificity in a metalloenzyme. Nat Commun. 2020;11 (1):2738. doi: 10.1038/s41467-020-16478-0. PubMed PMID:32483131 PubMed Central PMC7264356.
  40. Madej, M, White, JBR, Nowakowska, Z, Rawson, S, Scavenius, C, Enghild, JJ et al.. Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis. Nat Microbiol. 2020;5 (8):1016-1025. doi: 10.1038/s41564-020-0716-y. PubMed PMID:32393857 PubMed Central PMC7610489.
  41. Vollmar, M, Parkhurst, JM, Jaques, D, Baslé, A, Murshudov, GN, Waterman, DG et al.. The predictive power of data-processing statistics. IUCrJ. 2020;7 (Pt 2):342-354. doi: 10.1107/S2052252520000895. PubMed PMID:32148861 PubMed Central PMC7055369.
  42. Crawshaw, AD, Baslé, A, Salgado, PS. A practical overview of molecular replacement: Clostridioides difficile PilA1, a difficult case study. Acta Crystallogr D Struct Biol. 2020;76 (Pt 3):261-271. doi: 10.1107/S2059798320000467. PubMed PMID:32133990 PubMed Central PMC7057214.
  43. Ndeh, D, Baslé, A, Strahl, H, Yates, EA, McClurgg, UL, Henrissat, B et al.. Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus. Nat Commun. 2020;11 (1):646. doi: 10.1038/s41467-020-14509-4. PubMed PMID:32005816 PubMed Central PMC6994673.
  44. Cartmell, A, Muñoz-Muñoz, J, Briggs, JA, Ndeh, DA, Lowe, EC, Baslé, A et al.. Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nat Microbiol. 2019;4 (11):2021-2023. doi: 10.1038/s41564-019-0584-5. PubMed PMID:31541200 .
  45. Briliūtė, J, Urbanowicz, PA, Luis, AS, Baslé, A, Paterson, N, Rebello, O et al.. Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019;4 (9):1571-1581. doi: 10.1038/s41564-019-0466-x. PubMed PMID:31160824 PubMed Central PMC7617214.
  46. Labourel, A, Baslé, A, Munoz-Munoz, J, Ndeh, D, Booth, S, Nepogodiev, SA et al.. Structural and functional analyses of glycoside hydrolase 138 enzymes targeting chain A galacturonic acid in the complex pectin rhamnogalacturonan II. J Biol Chem. 2019;294 (19):7711-7721. doi: 10.1074/jbc.RA118.006626. PubMed PMID:30877196 PubMed Central PMC6514610.
  47. Fleming, JR, Schupfner, M, Busch, F, Baslé, A, Ehrmann, A, Sterner, R et al.. Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole. J Mol Biol. 2018;430 (24):5066-5079. doi: 10.1016/j.jmb.2018.10.013. PubMed PMID:30367843 .
  48. Cartmell, A, Muñoz-Muñoz, J, Briggs, JA, Ndeh, DA, Lowe, EC, Baslé, A et al.. A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nat Microbiol. 2018;3 (11):1314-1326. doi: 10.1038/s41564-018-0258-8. PubMed PMID:30349080 PubMed Central PMC6217937.
  49. Abellón-Ruiz, J, Zahn, M, Baslé, A, van den Berg, B. Crystal structure of the Acinetobacter baumannii outer membrane protein Omp33. Acta Crystallogr D Struct Biol. 2018;74 (Pt 9):852-860. doi: 10.1107/S205979831800904X. PubMed PMID:30198896 .
  50. Pathania, M, Acosta-Gutierrez, S, Bhamidimarri, SP, Baslé, A, Winterhalter, M, Ceccarelli, M et al.. Unusual Constriction Zones in the Major Porins OmpU and OmpT from Vibrio cholerae. Structure. 2018;26 (5):708-721.e4. doi: 10.1016/j.str.2018.03.010. PubMed PMID:29657131 .
  51. Ndeh, D, Rogowski, A, Cartmell, A, Luis, AS, Baslé, A, Gray, J et al.. Corrigendum: Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature. 2017;548 (7669):612. doi: 10.1038/nature23659. PubMed PMID:29411780 .
  52. Baslé, A, El Ghazouani, A, Lee, J, Dennison, C. Insight into Metal Removal from Peptides that Sequester Copper for Methane Oxidation. Chemistry. 2018;24 (18):4515-4518. doi: 10.1002/chem.201706035. PubMed PMID:29365216 PubMed Central PMC5947558.
  53. Aunkham, A, Zahn, M, Kesireddy, A, Pothula, KR, Schulte, A, Baslé, A et al.. Structural basis for chitin acquisition by marine Vibrio species. Nat Commun. 2018;9 (1):220. doi: 10.1038/s41467-017-02523-y. PubMed PMID:29335469 PubMed Central PMC5768706.
  54. Barwinska-Sendra, A, Baslé, A, Waldron, KJ, Un, S. A charge polarization model for the metal-specific activity of superoxide dismutases. Phys Chem Chem Phys. 2018;20 (4):2363-2372. doi: 10.1039/c7cp06829h. PubMed PMID:29308487 PubMed Central PMC5901066.
  55. Unterlass, JE, Wood, RJ, Baslé, A, Tucker, J, Cano, C, Noble, MME et al.. Structural insights into the enzymatic activity and potential substrate promiscuity of human 3-phosphoglycerate dehydrogenase (PHGDH). Oncotarget. 2017;8 (61):104478-104491. doi: 10.18632/oncotarget.22327. PubMed PMID:29262655 PubMed Central PMC5732821.
  56. Luis, AS, Briggs, J, Zhang, X, Farnell, B, Ndeh, D, Labourel, A et al.. Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol. 2018;3 (2):210-219. doi: 10.1038/s41564-017-0079-1. PubMed PMID:29255254 PubMed Central PMC5784806.
  57. Baslé, A, Hewitt, L, Koh, A, Lamb, HK, Thompson, P, Burgess, JG et al.. Crystal structure of NucB, a biofilm-degrading endonuclease. Nucleic Acids Res. 2018;46 (1):473-484. doi: 10.1093/nar/gkx1170. PubMed PMID:29165717 PubMed Central PMC5758888.
  58. Abellón-Ruiz, J, Kaptan, SS, Baslé, A, Claudi, B, Bumann, D, Kleinekathöfer, U et al.. Structural basis for maintenance of bacterial outer membrane lipid asymmetry. Nat Microbiol. 2017;2 (12):1616-1623. doi: 10.1038/s41564-017-0046-x. PubMed PMID:29038444 .
  59. Kryshtafovych, A, Albrecht, R, Baslé, A, Bule, P, Caputo, AT, Carvalho, AL et al.. Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016). Proteins. 2018;86 Suppl 1 (Suppl 1):27-50. doi: 10.1002/prot.25392. PubMed PMID:28960539 PubMed Central PMC5820184.
  60. Munoz-Munoz, J, Cartmell, A, Terrapon, N, Baslé, A, Henrissat, B, Gilbert, HJ et al.. An evolutionarily distinct family of polysaccharide lyases removes rhamnose capping of complex arabinogalactan proteins. J Biol Chem. 2017;292 (32):13271-13283. doi: 10.1074/jbc.M117.794578. PubMed PMID:28637865 PubMed Central PMC5555188.
  61. Cartmell, A, Lowe, EC, Baslé, A, Firbank, SJ, Ndeh, DA, Murray, H et al.. How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans. Proc Natl Acad Sci U S A. 2017;114 (27):7037-7042. doi: 10.1073/pnas.1704367114. PubMed PMID:28630303 PubMed Central PMC5502631.
  62. Baslé, A, Platsaki, S, Dennison, C. Visualizing Biological Copper Storage: The Importance of Thiolate-Coordinated Tetranuclear Clusters. Angew Chem Int Ed Engl. 2017;56 (30):8697-8700. doi: 10.1002/anie.201703107. PubMed PMID:28504850 PubMed Central PMC5519932.
  63. Temple, MJ, Cuskin, F, Baslé, A, Hickey, N, Speciale, G, Williams, SJ et al.. A Bacteroidetes locus dedicated to fungal 1,6-β-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-β-glucanase. J Biol Chem. 2017;292 (25):10639-10650. doi: 10.1074/jbc.M117.787606. PubMed PMID:28461332 PubMed Central PMC5481569.
  64. Ndeh, D, Rogowski, A, Cartmell, A, Luis, AS, Baslé, A, Gray, J et al.. Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature. 2017;544 (7648):65-70. doi: 10.1038/nature21725. PubMed PMID:28329766 PubMed Central PMC5388186.
  65. Glenwright, AJ, Pothula, KR, Bhamidimarri, SP, Chorev, DS, Baslé, A, Firbank, SJ et al.. Structural basis for nutrient acquisition by dominant members of the human gut microbiota. Nature. 2017;541 (7637):407-411. doi: 10.1038/nature20828. PubMed PMID:28077872 PubMed Central PMC5497811.
  66. Vita, N, Landolfi, G, Baslé, A, Platsaki, S, Lee, J, Waldron, KJ et al.. Bacterial cytosolic proteins with a high capacity for Cu(I) that protect against copper toxicity. Sci Rep. 2016;6 :39065. doi: 10.1038/srep39065. PubMed PMID:27991525 PubMed Central PMC5171941.
  67. Unterlass, JE, Baslé, A, Blackburn, TJ, Tucker, J, Cano, C, Noble, MEM et al.. Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget. 2018;9 (17):13139-13153. doi: 10.18632/oncotarget.11487. PubMed PMID:29568346 PubMed Central PMC5862567.
  68. Labourel, A, Crouch, LI, Brás, JL, Jackson, A, Rogowski, A, Gray, J et al.. The Mechanism by Which Arabinoxylanases Can Recognize Highly Decorated Xylans. J Biol Chem. 2016;291 (42):22149-22159. doi: 10.1074/jbc.M116.743948. PubMed PMID:27531750 PubMed Central PMC5063996.
  69. Arunmanee, W, Pathania, M, Solovyova, AS, Le Brun, AP, Ridley, H, Baslé, A et al.. Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis. Proc Natl Acad Sci U S A. 2016;113 (34):E5034-43. doi: 10.1073/pnas.1602382113. PubMed PMID:27493217 PubMed Central PMC5003275.
  70. Venditto, I, Luis, AS, Rydahl, M, Schückel, J, Fernandes, VO, Vidal-Melgosa, S et al.. Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition. Proc Natl Acad Sci U S A. 2016;113 (26):7136-41. doi: 10.1073/pnas.1601558113. PubMed PMID:27298375 PubMed Central PMC4932953.
  71. van den Berg, B, Chembath, A, Jefferies, D, Basle, A, Khalid, S, Rutherford, JC et al.. Structural basis for Mep2 ammonium transceptor activation by phosphorylation. Nat Commun. 2016;7 :11337. doi: 10.1038/ncomms11337. PubMed PMID:27088325 PubMed Central PMC4852598.
  72. Rogowski, A, Briggs, JA, Mortimer, JC, Tryfona, T, Terrapon, N, Lowe, EC et al.. Corrigendum: Glycan complexity dictates microbial resource allocation in the large intestine. Nat Commun. 2016;7 :10705. doi: 10.1038/ncomms10705. PubMed PMID:26848059 PubMed Central PMC4748232.
  73. Zahn, M, Bhamidimarri, SP, Baslé, A, Winterhalter, M, van den Berg, B. Structural Insights into Outer Membrane Permeability of Acinetobacter baumannii. Structure. 2016;24 (2):221-31. doi: 10.1016/j.str.2015.12.009. PubMed PMID:26805524 .
  74. Kryshtafovych, A, Moult, J, Baslé, A, Burgin, A, Craig, TK, Edwards, RA et al.. Some of the most interesting CASP11 targets through the eyes of their authors. Proteins. 2016;84 Suppl 1 (Suppl Suppl 1):34-50. doi: 10.1002/prot.24942. PubMed PMID:26473983 PubMed Central PMC4834066.
  75. Vita, N, Platsaki, S, Baslé, A, Allen, SJ, Paterson, NG, Crombie, AT et al.. A four-helix bundle stores copper for methane oxidation. Nature. 2015;525 (7567):140-3. doi: 10.1038/nature14854. PubMed PMID:26308900 PubMed Central PMC4561512.
  76. Cuskin, F, Baslé, A, Ladevèze, S, Day, AM, Gilbert, HJ, Davies, GJ et al.. The GH130 Family of Mannoside Phosphorylases Contains Glycoside Hydrolases That Target β-1,2-Mannosidic Linkages in Candida Mannan. J Biol Chem. 2015;290 (41):25023-33. doi: 10.1074/jbc.M115.681460. PubMed PMID:26286752 PubMed Central PMC4599007.
  77. Rogowski, A, Briggs, JA, Mortimer, JC, Tryfona, T, Terrapon, N, Lowe, EC et al.. Glycan complexity dictates microbial resource allocation in the large intestine. Nat Commun. 2015;6 :7481. doi: 10.1038/ncomms8481. PubMed PMID:26112186 PubMed Central PMC4491172.
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