Paula Salgado’s Publications

  1. Latimer-Smith, M, Salgado, PS, Forsyth, I, Makeyev, E, Poranen, MM, Stuart, DI et al.. Structure of the RNA-dependent RNA polymerase P2 from the cystovirus φ8. Sci Rep. 2024;14 (1):23540. doi: 10.1038/s41598-024-75213-7. PubMed PMID:39384884 PubMed Central PMC11464883.
  2. Martins, D, Nerber, HN, Roughton, CG, Fasquelle, A, Barwinska-Sendra, A, Vollmer, D et al.. Cleavage of an engulfment peptidoglycan hydrolase by a sporulation signature protease in Clostridioides difficile. Mol Microbiol. 2024;122 (2):213-229. doi: 10.1111/mmi.15291. PubMed PMID:38922761 PubMed Central PMC11309906.
  3. Ormsby, MJ, Vaz, F, Kirk, JA, Barwinska-Sendra, A, Hallam, JC, Lanzoni-Mangutchi, P et al.. An intact S-layer is advantageous to Clostridioides difficile within the host. PLoS Pathog. 2023;19 (6):e1011015. doi: 10.1371/journal.ppat.1011015. PubMed PMID:37384772 PubMed Central PMC10310040.
  4. Lima, LC, Costa, ACD, Salgado, PS, Onoue, ACF. ANATOMICAL STUDY OF VOLAR FACE OF DISTAL RADIUS AND COMPARISON WITH THE SHAPE OF LOCKING VOLAR PLATES. Acta Ortop Bras. 2022;30 (5):e257953. doi: 10.1590/1413-785220223005e257953. PubMed PMID:36451793 PubMed Central PMC9670780.
  5. Lanzoni-Mangutchi, P, Banerji, O, Wilson, J, Barwinska-Sendra, A, Kirk, JA, Vaz, F et al.. Structure and assembly of the S-layer in C. difficile. Nat Commun. 2022;13 (1):970. doi: 10.1038/s41467-022-28196-w. PubMed PMID:35217634 PubMed Central PMC8881574.
  6. Julius, C, Salgado, PS, Yuzenkova, Y. Metabolic cofactors NADH and FAD act as non-canonical initiating substrates for a primase and affect replication primer processing in vitro. Nucleic Acids Res. 2020;48 (13):7298-7306. doi: 10.1093/nar/gkaa447. PubMed PMID:32463447 PubMed Central PMC7367122.
  7. Crawshaw, AD, Baslé, A, Salgado, PS. A practical overview of molecular replacement: Clostridioides difficile PilA1, a difficult case study. Acta Crystallogr D Struct Biol. 2020;76 (Pt 3):261-271. doi: 10.1107/S2059798320000467. PubMed PMID:32133990 PubMed Central PMC7057214.
  8. Kelly, A, Salgado, PS. The engulfasome in C. difficile: Variations on protein machineries. Anaerobe. 2019;60 :102091. doi: 10.1016/j.anaerobe.2019.102091. PubMed PMID:31470088 PubMed Central PMC6934232.
  9. Dembek, M, Kelly, A, Barwinska-Sendra, A, Tarrant, E, Stanley, WA, Vollmer, D et al.. Peptidoglycan degradation machinery in Clostridium difficile forespore engulfment. Mol Microbiol. 2018;110 (3):390-410. doi: 10.1111/mmi.14091. PubMed PMID:30066424 PubMed Central PMC6221140.
  10. Herrero-de-Dios, C, Day, AM, Tillmann, AT, Kastora, SL, Stead, D, Salgado, PS et al.. Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs. mBio. 2018;9 (2):. doi: 10.1128/mBio.02229-17. PubMed PMID:29588408 PubMed Central PMC5874921.
  11. Dembek, M, Willing, SE, Hong, HA, Hosseini, S, Salgado, PS, Cutting, SM et al.. Inducible Expression of spo0A as a Universal Tool for Studying Sporulation in Clostridium difficile. Front Microbiol. 2017;8 :1793. doi: 10.3389/fmicb.2017.01793. PubMed PMID:28983286 PubMed Central PMC5613124.
  12. Serrano, M, Crawshaw, AD, Dembek, M, Monteiro, JM, Pereira, FC, Pinho, MG et al.. The SpoIIQ-SpoIIIAH complex of Clostridium difficile controls forespore engulfment and late stages of gene expression and spore morphogenesis. Mol Microbiol. 2016;100 (1):204-28. doi: 10.1111/mmi.13311. PubMed PMID:26690930 PubMed Central PMC4982068.
  13. Warren, AJ, Crawshaw, AD, Trincao, J, Aller, P, Alcock, S, Nistea, I et al.. In vacuo X-ray data collection from graphene-wrapped protein crystals. Acta Crystallogr D Biol Crystallogr. 2015;71 (Pt 10):2079-88. doi: 10.1107/S1399004715014194. PubMed PMID:26457431 PubMed Central PMC4601369.
  14. Crawshaw, AD, Serrano, M, Stanley, WA, Henriques, AO, Salgado, PS. A mother cell-to-forespore channel: current understanding and future challenges. FEMS Microbiol Lett. 2014;358 (2):129-36. doi: 10.1111/1574-6968.12554. PubMed PMID:25105965 .
  15. Lin, J, Oh, SH, Jones, R, Garnett, JA, Salgado, PS, Rusnakova, S et al.. The peptide-binding cavity is essential for Als3-mediated adhesion of Candida albicans to human cells. J Biol Chem. 2014;289 (26):18401-12. doi: 10.1074/jbc.M114.547877. PubMed PMID:24802757 PubMed Central PMC4140257.
  16. Douse, CH, Green, JL, Salgado, PS, Simpson, PJ, Thomas, JC, Langsley, G et al.. Regulation of the Plasmodium motor complex: phosphorylation of myosin A tail-interacting protein (MTIP) loosens its grip on MyoA. J Biol Chem. 2012;287 (44):36968-77. doi: 10.1074/jbc.M112.379842. PubMed PMID:22932904 PubMed Central PMC3481298.
  17. Salgado, PS, Yan, R, Taylor, JD, Burchell, L, Jones, R, Hoyer, LL et al.. Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans. Proc Natl Acad Sci U S A. 2011;108 (38):15775-9. doi: 10.1073/pnas.1103496108. PubMed PMID:21896717 PubMed Central PMC3179088.
  18. Taylor, JD, Zhou, Y, Salgado, PS, Patwardhan, A, McGuffie, M, Pape, T et al.. Atomic resolution insights into curli fiber biogenesis. Structure. 2011;19 (9):1307-16. doi: 10.1016/j.str.2011.05.015. PubMed PMID:21893289 PubMed Central PMC3173608.
  19. Salgado, PS, Yan, R, Rowan, F, Cota, E. Expression, crystallization and preliminary X-ray data analysis of NT-Als9-2, a fungal adhesin from Candida albicans. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011;67 (Pt 4):467-70. doi: 10.1107/S1744309111003460. PubMed PMID:21505243 PubMed Central PMC3080152.
  20. Salgado, PS, Taylor, JD, Cota, E, Matthews, SJ. Extending the usability of the phasing power of diselenide bonds: SeCys SAD phasing of CsgC using a non-auxotrophic strain. Acta Crystallogr D Biol Crystallogr. 2011;67 (Pt 1):8-13. doi: 10.1107/S0907444910042022. PubMed PMID:21206057 PubMed Central PMC3522112.
  21. Poranen, MM, Salgado, PS, Koivunen, MR, Wright, S, Bamford, DH, Stuart, DI et al.. Structural explanation for the role of Mn2+ in the activity of phi6 RNA-dependent RNA polymerase. Nucleic Acids Res. 2008;36 (20):6633-44. doi: 10.1093/nar/gkn632. PubMed PMID:18940872 PubMed Central PMC2582606.
  22. Salgado, PS, Koivunen, MR, Makeyev, EV, Bamford, DH, Stuart, DI, Grimes, JM et al.. The structure of an RNAi polymerase links RNA silencing and transcription. PLoS Biol. 2006;4 (12):e434. doi: 10.1371/journal.pbio.0040434. PubMed PMID:17147473 PubMed Central PMC1750930.
  23. Laurila, MRL, Salgado, PS, Stuart, DI, Grimes, JM, Bamford, DH. Back-priming mode of phi6 RNA-dependent RNA polymerase. J Gen Virol. 2005;86 (Pt 2):521-526. doi: 10.1099/vir.0.80492-0. PubMed PMID:15659773 .
  24. Laurila, MR, Salgado, PS, Makeyev, EV, Nettelship, J, Stuart, DI, Grimes, JM et al.. Gene silencing pathway RNA-dependent RNA polymerase of Neurospora crassa: yeast expression and crystallization of selenomethionated QDE-1 protein. J Struct Biol. 2005;149 (1):111-5. doi: 10.1016/j.jsb.2004.10.001. PubMed PMID:15629662 .
  25. Salgado, PS, Walsh, MA, Laurila, MR, Stuart, DI, Grimes, JM. Going soft and SAD with manganese. Acta Crystallogr D Biol Crystallogr. 2005;61 (Pt 1):108-11. doi: 10.1107/S0907444904026800. PubMed PMID:15608382 .
  26. Salgado, PS, Makeyev, EV, Butcher, SJ, Bamford, DH, Stuart, DI, Grimes, JM et al.. The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure. 2004;12 (2):307-16. doi: 10.1016/j.str.2004.01.012. PubMed PMID:14962391 .
  27. RATNER, B, ROSTLER, AE, SALGADO, PS. Care, feeding and fate of premature and full term infants born of tuberculous mothers. AMA Am J Dis Child. 1951;81 (4):471-82. doi: 10.1001/archpedi.1951.02040030482002. PubMed PMID:14810178 .
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